Rabbit anti-Human E-Selectin/SELE monoclonal antibody

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£347.65

War £409.00

SKU:: RM98003
Zusätzliche Namen:: CD62E|ELAM|ELAM1|ESEL|LECAM2|selectin-e
Anwendung:: ELISA
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Abclonal
Immunogen:: Recombinant Human E-Selectin/SELE Protein
Formulierung:: Supplied as a 0.2um filtered solution in PBS with 0.05% Proclin300, PH 7.4.
Spezies:: Human
Uniprot:: P16581
Synonyme:: CD62 antigen-like family member E;CD62E;E-selectin;ELAM;ELAM-1;ELAM1;endothelial adhesion molecule 1;endothelial leukocyte adhesion molecule 1;ESEL;LECAM2;leukocyte endothelial cell adhesion molecule 2;Leukocyte-endothelial cell adhesion molecule 2
Weitere Details:: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.