Rabbit anti-Human Soluble Tyrosine-protein kinase receptor UFO(sAXL) monoclonal antibody

Größe

£372.30

War £438.00

SKU:: RM17989
Zusätzliche Namen:: ARK|JTK11|Tyro7|UFO
Anwendung:: ELISA
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Abclonal
Immunogen:: Recombinant Human AXL
Formulierung:: Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
Spezies:: Human
Uniprot:: P30530
Synonyme:: ARK;AXL oncogene;AXL transforming sequence/gene;JTK11;Tyro7;tyrosine-protein kinase receptor UFO;UFO
Weitere Details:: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus.