Rabbit anti-Mouse TNF-A Alpha monoclonal antibody(CAP)

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£347.65

War £409.00

SKU:: RM17969
Zusätzliche Namen:: DIF|TNF-a|TNF-alpha|Tnfa|TNFalpha|Tnfsf1a|TNFSF2|Tnlg1f
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Abclonal
Reaktivitäten:: Mouse
Immunogen:: Recombinant Mouse TNF-A Alpha Protein
Formulierung:: Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.3.
Spezies:: Mouse
Uniprot:: P06804
Synonyme:: cachectin;DI;DIF;Tn;TNF-;TNF-a;TNF-alpha;Tnfa;TNFalpha;Tnfs;Tnfsf1a;TNFSF2;Tnlg1f;tumor necrosis factor;tumor necrosis factor ligand 1f;tumor necrosis factor ligand superfamily member 2;tumor necrosis factor-alpha
Weitere Details:: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This protein is synthesized as a type-II transmembrane protein and is reported to be cleaved into products that exert distinct biological functions. It plays an important role in the innate immune response as well as regulating homeostasis but is also implicated in diseases of chronic inflammation. In mouse deficiency of this gene is associated with defects in response to bacterial infection, with defects in forming organized follicular dendritic cell networks and germinal centers, and with a lack of primary B cell follicles. Alternative splicing results in multiple transcript variants.