Rabbit anti-Human NEFL monoclonal antibody (CAP)

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£372.30

War £438.00

SKU:: RM17782
Zusätzliche Namen:: CMT1F|CMT2E|CMTDIG|NF-L|NF68|NFL|PPP1R110
Anwendung:: ELISA
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C
Hersteller:: Abclonal
Immunogen:: Recombinant Human NEFL Protein
Formulierung:: Supplied as a 0.2 um filtered solution in PBS with 0.05% Proclin 300, pH 7.3.
Spezies:: Human
Uniprot:: P07196
Synonyme:: 68 kDa neurofilament protein;CMT1F;CMT2E;CMTDIG;light molecular weight neurofilament protein;neurofilament light polypeptide;neurofilament protein, light chain;neurofilament subunit NF-L;neurofilament triplet L protein;neurofilament, light polypeptide 68kDa;NF-L;NF68;NFL;PPP1R110;protein phosphatase 1, regulatory subunit 110
Weitere Details:: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.