MRC2 Rabbit polyclonal antibody

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£151.00

SKU:: A9858
Zusätzliche Namen:: CD280|CLEC13E|ENDO180|MRC2|UPARAP
Anwendung:: ELISA, WB
Molekulargewicht:: 190kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: RWHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL
Uniprot:: Q9UBG0
Synonyme:: C-type lectin domain family 13 member E;C-type mannose receptor 2;CD280;CLEC13E;ENDO180;endocytic receptor (macrophage mannose receptor family);endocytic receptor 180;macrophage mannose receptor 2;UPAR-associated protein;UPARAP;urokinase-type plasminogen activator receptor-associated protein
Weitere Details:: This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.