MKL1 Rabbit polyclonal antibody

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£151.00

SKU:: A8504
Zusätzliche Namen:: BSAC|MAL|MKL|MKL1|MRTF-A
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 145kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEETSAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVADSSSFDEDSSDALSPEQPASHESQGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQPPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSASEKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDRGAPPMDSSYAKILQQQQLFLQLQILNQQQQ
Uniprot:: Q969V6
Synonyme:: basic, SAP and coiled-coil domain;BSAC;MAL;megakaryoblastic leukemia (translocation) 1;megakaryoblastic leukemia 1 protein;megakaryocytic acute leukemia protein;MKL;MKL/myocardin-like protein 1;MKL1;MRTF-A;myocardin-related transcription factor A
Weitere Details:: The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants.

Versandbedingungen:: Blue Ice