A8451
DNA Polymerase gamma Rabbit polyclonal antibody
Größe
£151.00
- SKU:
- A8451
- Zusätzliche Namen:
- DNA Polymerase gamma|MDP1|MIRAS|MTDPS4A|MTDPS4B|PEO|POLG1|POLGA|SANDO|SCAE
- Anwendung:
- ELISA, WB
- Molekulargewicht:
- 140kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- QQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEQGKQQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALT
- Uniprot:
- P54098
- Synonyme:
- DNA polymerase subunit gamma-1;MDP1;MIRAS;mitochondrial DNA polymerase catalytic subunit;mitochondrial polymerase gamma catalytic subunit;MTDPS4A;MTDPS4B;PEO;PolG-alpha;POLG1;POLGA;polymerase (DNA directed), gamma;polymerase (DNA) gamma, catalytic subunit;SANDO;SCAE;truncated mitochondrial DNA polymerase gamma catalytic subunit;truncated mitochondrial polymerase gamma catalytic subunit
- Weitere Details:
- Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.
- Versandbedingungen:
- Blue Ice