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A8426

GTF3A Rabbit polyclonal antibody

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£151.00

SKU:
A8426
Zusätzliche Namen:
AP2|GTF3A|TFIIIA
Anwendung:
ELISA, WB
Molekulargewicht:
40kda
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
MDPPAVVAESVSSLTIADAFIAAGESSAPTPPRPALPRRFICSFPDCSANYSKAWKLDAHLCKHTGERPFVCDYEGCGKAFIRDYHLSRHILTHTGEKPF
Uniprot:
Q92664
Synonyme:
AP2;TFIIIA;transcription factor IIIA
Weitere Details:
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.
Versandbedingungen:
Blue Ice