PHD3 Rabbit polyclonal antibody

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£152.00

SKU:: A8001
Zusätzliche Namen:: HIFP4H3|HIFPH3|PHD3
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 32kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDR
Uniprot:: Q9H6Z9
Synonyme:: HIF-PH3;HIF-prolyl hydroxylase 3;HIFP4H3;HIFPH3;HPH-1;HPH-3;hypoxia-inducible factor prolyl hydroxylase 3;PHD3;prolyl hydroxylase domain-containing protein 3;prolyl hydroxylase EGLN3
Weitere Details:: Enables peptidyl-proline 4-dioxygenase activity. Involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; and response to hypoxia. Located in cytosol and nucleus. Implicated in renal cell carcinoma. Biomarker of clear cell renal cell carcinoma.