A7919
PLOD1 Rabbit polyclonal antibody
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£152.00
- SKU:
- A7919
- Zusätzliche Namen:
- EDS6|EDSKCL1|LH|LH1|LLH|PLOD|PLOD1
- Anwendung:
- ELISA, WB
- Molekulargewicht:
- 84kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- KGDAKPEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWNVEKGTSAGGGQKVRLLKKALEKHADKEDLVILFADSYDVLFASGPRELLKKFRQARSQVVFSAEELIYPDRRLETKYPVVSDGKRFLGSGGFIGYAPNLSKLVAEWEGQDSDSDQLFYTKIFLDPEKREQINITLDHRCRIFQNLDGALDEVVLKFEMGHVRARNLAYDTLPVLIHGNGPTKLQLNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIE
- Uniprot:
- Q02809
- Synonyme:
- EDS6;EDSKCL1;LH;LH1;LLH;lysine hydroxylase;lysyl hydroxlase 1;Lysyl hydroxylase 1;PLOD;procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1;procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
- Weitere Details:
- Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice