TBL1XR1 Rabbit polyclonal antibody

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£152.00

SKU:: A7834
Zusätzliche Namen:: C21|DC42|IRA1|MRD41|TBL1XR1|TBLR1
Anwendung:: ELISA, WB
Molekulargewicht:: 60kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV
Uniprot:: Q9BZK7
Synonyme:: C21;DC42;F-box-like/WD repeat-containing protein TBL1XR1;IRA1;MRD41;nuclear receptor co-repressor/HDAC3 complex subunit;nuclear receptor corepressor/HDAC3 complex subunit TBLR1;TBL1-related protein 1;TBLR1;transducin beta like 1 X-linked receptor 1;Transducin beta-like 1X-related protein 1
Weitere Details:: This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.

Versandbedingungen:: Blue Ice