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A7469

COQ3 Rabbit polyclonal antibody

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£152.00

SKU:
A7469
Zusätzliche Namen:
bA9819.1|COQ3|DHHBMT|DHHBMTASE|UG0215E05
Anwendung:
ELISA, WB, IF, ICC
Molekulargewicht:
32kDa/41kDa
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
PGVFNEYRTIWFKSYRTIFSCLNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQIASIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAYAVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
Uniprot:
Q9NZJ6
Synonyme:
2-polyprenyl-6-hydroxyphenol methylase;2-polyprenyl-6-hydroxyphenyl methylase;3-demethylubiquinol 3-O-methyltransferase;3-demethylubiquinone-10 3-methyltransferase;3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase;bA9819.1;coenzyme Q3 homolog, methyltransferase;DHHB methyltransferase;DHHB-MTase;DHHBMT;DHHBMTASE;dihydroxyhexaprenylbenzoate methyltransferase;hexaprenyldihydroxybenzoate methyltransferase, mitochondrial;methyltransferase COQ3;polyprenyldihydroxybenzoate methyltransferase;ubiquinone biosynthesis O-methyltransferase, mitochondrial;UG0215E05
Weitere Details:
Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
Versandbedingungen:
Blue Ice