A7228
ABCA1 Rabbit polyclonal antibody
Größe
£152.00
- SKU:
- A7228
- Zusätzliche Namen:
- ABC-1|ABC1|ABCA1|CERP|HDLCQTL13|HDLDT1|HPALP1|TGD
- Anwendung:
- ELISA, WB, IF, ICC
- Molekulargewicht:
- 254 kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Uniprot:
- O95477
- Synonyme:
- ABC-1;ABC1;ATP-binding cassette sub-family A member 1;ATP-binding cassette transporter 1;ATP-binding cassette transporter A1;ATP-binding cassette, sub-family A (ABC1), member 1;CERP;cholesterol efflux regulatory protein;HDLCQTL13;HDLDT1;HPALP1;membrane-bound;phospholipid-transporting ATPase ABCA1;TGD
- Weitere Details:
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency.
- Versandbedingungen:
- Blue Ice