A7082
ISCU Rabbit polyclonal antibody
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£152.00
- SKU:
- A7082
- Zusätzliche Namen:
- 2310020H20Rik|HML|hnifU|ISCU|ISU2|NIFU|NIFUN
- Anwendung:
- ELISA, WB
- Molekulargewicht:
- 14-18kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- MAAAGAFRLRRAASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK
- Uniprot:
- Q9H1K1
- Synonyme:
- 2310020H20Rik;HML;hnifU;iron-sulfur cluster assembly enzyme ISCU, mitochondrial;IscU iron-sulfur cluster scaffold homolog;ISU2;NIFU;nifU-like N-terminal domain-containing protein;NifU-like protein;NIFUN
- Weitere Details:
- This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.
- Versandbedingungen:
- Blue Ice