HAND2 Rabbit polyclonal antibody

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£152.00

SKU:: A7044
Zusätzliche Namen:: bHLHa26|dHand|DHAND2|HAND2|Hed|Thing2
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 26 kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: LMDLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKGRTGWPQHVWALELKQ
Uniprot:: P61296
Synonyme:: basic helix-loop-helix transcription factor HAND2;bHLHa26;class A basic helix-loop-helix protein 26;deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2;dHand;DHAND2;heart- and neural crest derivatives-expressed protein 2;Hed;Thing2
Weitere Details:: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.