MECOM Rabbit polyclonal antibody

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£152.00

SKU:: A5674
Zusätzliche Namen:: AML1-EVI-1|EVI1|KMT8E|MDS1|MDS1-EVI1|MECOM|PRDM3|RUSAT2
Anwendung:: ELISA, WB
Molekulargewicht:: 105kDa/145kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MRSKGRARKLATNNECVYGNYPEIPLEEMPDADGVASTPSLNIQEPCSPATSSEAFTPKEGSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWTKRKIEVGEKFGPYVGEQRSNLKDPSYGWEILDEFYNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVADIAPGEELLLFMK
Uniprot:: Q03112, Q13465
Synonyme:: AML1-EVI-1;AML1-EVI-1 fusion protein;ecotropic virus integration site 1 protein homolog;EVI1;histone-lysine N-methyltransferase MECOM;KMT8E;MDS1;MDS1 and EVI1 complex locus protein EVI1;MDS1 and EVI1 complex locus protein MDS1;MDS1-EVI1;Myelodysplasia syndrome 1 protein;myelodysplasia syndrome-associated protein 1;oncogene EVI1;PR domain 3;PRDM3;RUSAT2;zinc finger protein Evi1
Weitere Details:: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

Versandbedingungen:: Blue Ice