SKIV2L2 Rabbit polyclonal antibody

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£152.00

SKU:: A5576
Zusätzliche Namen:: Dob1|fSAP118|KIAA0052|Mtr4|SKIV2L2
Anwendung:: ELISA, WB, IHC-P, IP
Molekulargewicht:: 123kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MADAFGDELFSVFEGDSTTAAGTKKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNGKNKRDVDFEGTDEPIFGKKPRIEESITEDLSLADLMPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPC
Uniprot:: P42285
Synonyme:: ATP-dependent helicase SKIV2L2;ATP-dependent RNA helicase DOB1;ATP-dependent RNA helicase SKIV2L2;Dob1;exosome RNA helicase MTR4;fSAP118;functional spliceosome-associated protein 118;KIAA0052;Mtr4;Ski2 like RNA helicase 2;SKIV2L2;superkiller viralicidic activity 2-like 2;TRAMP-like complex helicase
Weitere Details:: Enables ATP binding activity and RNA helicase activity. Involved in RNA catabolic process; cellular response to DNA damage stimulus; and maturation of 5.8S rRNA. Located in nucleoplasm. Part of TRAMP complex and catalytic step 2 spliceosome. Colocalizes with nuclear exosome (RNase complex). Biomarker of amyotrophic lateral sclerosis.