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A5559

ATIC Rabbit polyclonal antibody

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£152.00

SKU:
A5559
Zusätzliche Namen:
AICAR|AICARFT|ATIC|HEL-S-70p|IMPCHASE|PURH
Anwendung:
ELISA, WB
Molekulargewicht:
62kDa
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
Uniprot:
P31939
Synonyme:
5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase;AICAR;AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme;AICAR transformylase/inosine monophosphate cyclohydrolase;AICARFT;AICARFT/IMPCHASE;bifunctional purine biosynthesis protein ATIC;bifunctional purine biosynthesis protein PURH;epididymis secretory sperm binding protein Li 70p;HEL-S-70p;IMPCHASE;phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase;PURH
Weitere Details:
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
Versandbedingungen:
Blue Ice