LBR Rabbit polyclonal antibody

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SKU:: A5468
Zusätzliche Namen:: C14SR|DHCR14B|LBR|LMN2R|PHA|PHASK|TDRD18
Anwendung:: ELISA, WB, IF, ICC
Molekulargewicht:: 68kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: Q14739
Synonyme:: 3-beta-hydroxysterol Delta (14)-reductase;C-14 sterol reductase;C14SR;delta-14-SR;delta(14)-sterol reductase LBR;DHCR14B;integral nuclear envelope inner membrane protein;LMN2R;PHA;PHASK;sterol C14-reductase;TDRD18;tudor domain containing 18
Weitere Details:: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.