Caspase-2 Rabbit monoclonal antibody

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SKU:: A4888
Zusätzliche Namen:: CASP-2|Caspase-2|ICH1|NEDD-2|NEDD2|PPP1R57
Anwendung:: ELISA, WB
Molekulargewicht:: 14kDa/48kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: GKNHTQSPGCEESDAGKEELMKMRLPTRSDMICGYACLKGNAAMRNTKRGSWYIEALTQVFSERACDMHVADMLVKVNALIKEREGYAPGTEFHRCKEMSEYCSTLCQQLYLFPGYPPT
Uniprot:: P42575
Synonyme:: CASP-2;caspase 2 apoptosis-related cysteine peptidase;caspase-2;ICH1;NEDD-2;NEDD2;neural precursor cell expressed developmentally down-regulated protein 2;PPP1R57;protease ICH-1;protein phosphatase 1, regulatory subunit 57
Weitere Details:: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.