Coagulation Protein C Rabbit monoclonal antibody

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SKU:: A4532
Zusätzliche Namen:: APC|Coagulation Protein C|PC|PROC1|THPH3|THPH4
Anwendung:: ELISA, WB, IF
Molekulargewicht:: 52kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: IALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAP
Uniprot:: P04070
Synonyme:: activated protein C;anticoagulant protein C;APC;autoprothrombin IIA;blood coagulation factor XIV;PC;prepro-protein C;PROC1;Protein C-Nagoya;THPH3;THPH4;type I protein C;vitamin K-dependent protein C
Weitere Details:: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.