[KO Validated] ARHGEF1 Rabbit polyclonal antibody

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SKU:: A4274
Zusätzliche Namen:: F1|GEF1|IMD62|LBCL2|LSC|P115-RHOGEF|SUB1.5
Anwendung:: ELISA, WB, IHC-P
Molekulargewicht:: 115kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: PLLSSSENGNGGRETSPADARTERILSDLLPFCRPGPEGQLAATALRKVLSLKQLLFPAEEDNGAGPPRDGDGVPGGGPLSPARTQEIQENLLSLEETMKQLEELEEEFCRLRPLLSQLGGNSVPQPGCT
Uniprot:: Q92888
Synonyme:: 115 kDa guanine nucleotide exchange factor;115-kD protein;GEF1;IMD62;LBCL2;LSC;Lsc homolog;P115-RHOGEF;p115RhoGEF;Rho guanine nucleotide exchange factor (GEF) 1;rho guanine nucleotide exchange factor 1;SUB1.5
Weitere Details:: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.