NAE1 Rabbit polyclonal antibody

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£152.00

SKU:: A4254
Zusätzliche Namen:: A-116A10.1|APPBP1|HPP1|NAE1|NEDFIH|ula-1
Anwendung:: ELISA, WB
Molekulargewicht:: 60kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Sequenz:: MAQLGKLLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAK
Uniprot:: Q13564
Synonyme:: A-116A10.1;amyloid beta precursor protein binding protein 1, 59kDa;amyloid beta precursor protein-binding protein 1, 59 kDa;amyloid beta precursor protein-binding protein 1, 59kD;amyloid protein-binding protein 1;APP-BP1;APPBP1;HPP1;NEDD8-activating enzyme E1 regulatory subunit;NEDD8-activating enzyme E1 subunit;proto-oncogene protein 1;protooncogene protein 1;ula-1
Weitere Details:: The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Versandbedingungen:: Blue Ice