A4202
USP5 Rabbit polyclonal antibody
Größe
£152.00
- SKU:
- A4202
- Zusätzliche Namen:
- ISOT|USP5
- Anwendung:
- ELISA, WB, IHC-P, IF, ICC
- Molekulargewicht:
- 110kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFG
- Uniprot:
- P45974
- Synonyme:
- deubiquitinating enzyme 5;isopeptidase T;ISOT;testicular tissue protein Li 218;ubiquitin carboxyl-terminal hydrolase 5;ubiquitin isopeptidase T;ubiquitin specific protease 5 (isopeptidase T);ubiquitin thioesterase 5;ubiquitin thiolesterase 5;ubiquitin-specific protease-5 (ubiquitin isopeptidase T);ubiquitin-specific-processing protease 5
- Weitere Details:
- Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).
- Versandbedingungen:
- Blue Ice