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A4012

PDK2 Rabbit polyclonal antibody

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£152.00

SKU:
A4012
Zusätzliche Namen:
PDHK2|PDK2|PDKII
Anwendung:
ELISA, WB, IF, ICC
Molekulargewicht:
46kda
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Abclonal
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:
Unmodified
Sequenz:
PTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVYVPSHLYHMLFELFKNAMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPGTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS
Uniprot:
Q15119
Synonyme:
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial;PDH kinase 2;PDHK2;PDKII;Pyruvate dehydrogenase kinase isoform 2;pyruvate dehydrogenase kinase, isoenzyme 2;pyruvate dehydrogenase kinase, isozyme 2;pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial
Weitere Details:
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Versandbedingungen:
Blue Ice