A3194
SETD2 Rabbit polyclonal antibody
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£152.00
- SKU:
- A3194
- Zusätzliche Namen:
- HBP231|HIF-1|HIP-1|HSPC069|HYPB|KMT3A|LLS|MRD70|p231HBP|RAPAS|SET2|SETD2
- Anwendung:
- ELISA, WB, IHC-P, IF, ICC, IP
- Molekulargewicht:
- 288kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Sequenz:
- RKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE
- Uniprot:
- Q9BYW2
- Synonyme:
- HBP231;HIF-1;HIP-1;histone-lysine N-methyltransferase SETD2;HSPC069;huntingtin interacting protein 1;huntingtin yeast partner B;Huntingtin-interacting protein 1;huntingtin-interacting protein B;HYPB;KMT3A;LLS;lysine N-methyltransferase 3A;p231HBP;protein-lysine N-methyltransferase SETD2;SET domain-containing protein 2;SET2
- Weitere Details:
- Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
- Versandbedingungen:
- Blue Ice