CXCR3 Rabbit polyclonal antibody

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£151.00

SKU:: A2939
Zusätzliche Namen:: CD182|CD183|CKR-L2|CMKAR3|CXCR3|GPR9|IP10-R|Mig-R|MigR
Anwendung:: ELISA, WB, IHC-P
Molekulargewicht:: 44 kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Immunogen:: This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P49682
Synonyme:: C-X-C chemokine receptor type 3;CD182;CD183;chemokine (C-X-C motif) receptor 3;chemokine receptor 3;CKR-L2;CMKAR3;G protein-coupled receptor 9;GPR9;interferon-inducible protein 10 receptor;IP-10 receptor;IP10-R;Mig receptor;Mig-R;MigR
Weitere Details:: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).