TFEB Rabbit monoclonal antibody

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SKU:: A29007
Zusätzliche Namen:: bHLHe35|Tcfeb
Anwendung:: ELISA, WB, IF, ICC, IP
Molekulargewicht:: 65-70 kDa
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: Q9R210
Synonyme:: ALPHATFEB;bHLHe3;BHLHE35;class E basic helix-loop-helix protein 35;T-cell transcription factor EB;TCFEB;transcription factor EB
Weitere Details:: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Involved in several processes, including defense response to Gram-negative bacterium; embryonic placenta development; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within lysosome organization. Located in cytoplasm. Part of transcription regulator complex. Colocalizes with nucleus. Is expressed in several structures, including cardiovascular system; central nervous system; early conceptus; genitourinary system; and gut gland. Orthologous to human TFEB (transcription factor EB).