[KO Validated] STAT1 Rabbit monoclonal antibody

Größe

Auf Anfrage

SKU:: A28912
Zusätzliche Namen:: 2010005J02Rik
Anwendung:: ChIP, ELISA, WB, IHC-P, IF, ICC, IP
Molekulargewicht:: 84 kDa/91 kDa
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: Q8C3V4
Synonyme:: 2010005J02Rik;AA408197;CANDF7;IMD31A;IMD31B;IMD31C;ISGF-3;signal transducer and activator of transcription 1;signal transducer and activator of transcription 1-alpha/beta;signal transducer and activator of transcription 1, 91kD;signal transducer and activator of transcription 1, 91kDa;STAT91;transcription factor ISGF-3 components p91/p84
Weitere Details:: Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in cell population proliferation; cell surface receptor signaling pathway via JAK-STAT; and defense response to other organism. Acts upstream of or within with a positive effect on positive regulation of apoptotic process. Acts upstream of or within several processes, including cell surface receptor signaling pathway; negative regulation of macrophage fusion; and response to exogenous dsRNA. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and skeletal musculature. Used to study breast cancer and severe acute respiratory syndrome. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple); breast carcinoma; immunodeficiency 31A; immunodeficiency 31B; and immunodeficiency 31C. Orthologous to human STAT1 (signal transducer and activator of transcription 1).

Versandbedingungen:: Blue Ice