A28905
NOX2/gp91phox Rabbit monoclonal antibody
Größe
Auf Anfrage
- SKU:
- A28905
- Zusätzliche Namen:
- AMCBX2|CGD|CGDX|GP91-1|GP91-PHOX|GP91PHOX|IMD34|NOX2|p91-PHOX
- Anwendung:
- ELISA, WB, IHC-P, IF, IP
- Molekulargewicht:
- 65 kDa
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Uniprot:
- P04839
- Synonyme:
- AMCBX2;CGD;CGD91-phox;CGDX;cytochrome b-245 beta polypeptide;cytochrome b-245 heavy chain;cytochrome b(558) subunit beta;cytochrome b558 subunit beta;DBIL1;diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) pseudogene 2;diazepam binding inhibitor-like 1;diazepam binding inhibitor, acyl-CoA binding protein pseudogene 2;GP91-1;GP91-PHOX;GP91PHOX;heme-binding membrane glycoprotein gp91phox;IMD34;NADPH oxidase 2;neutrophil cytochrome b 91 kDa polypeptide;NOX2;p22 phagocyte B-cytochrome;p91-PHOX;superoxide-generating NADPH oxidase heavy chain subunit
- Weitere Details:
- Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
- Versandbedingungen:
- Blue Ice