A28903
PSD95 Rabbit monoclonal antibody
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- SKU:
- A28903
- Zusätzliche Namen:
- Dlgh4|PSD-95|PSD95|SAP90|SAP90A
- Anwendung:
- ELISA, WB, IHC-P, IF
- Molekulargewicht:
- 95 kDa/75 kDa
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Immunogen:
- This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Uniprot:
- Q62108
- Synonyme:
- discs large homolog 4;discs, large homolog 4;disks large homolog 4;Dlgh;Dlgh4;MRD62;post-synaptic density protein 95;postsynaptic density protein 95;PSD;PSD-;PSD-95;PSD-95 alpha 2b;PSD-95 beta;PSD95;SA;SAP-90;SAP90;SAP90A;synapse-associated protein 90;Tax interaction protein 15
- Weitere Details:
- Enables ionotropic glutamate receptor binding activity and scaffold protein binding activity. Involved in several processes, including dendritic spine morphogenesis; locomotory exploration behavior; and neurotransmitter receptor localization to postsynaptic specialization membrane. Acts upstream of or within protein localization to synapse; regulation of long-term neuronal synaptic plasticity; and synaptic vesicle maturation. Located in several cellular components, including axon; postsynaptic density; and synaptic vesicle. Part of AMPA glutamate receptor complex. Is active in glutamatergic synapse. Colocalizes with postsynaptic membrane. Is expressed in central nervous system; dorsal root ganglion; and sensory organ. Used to study Williams-Beuren syndrome and autism spectrum disorder. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 62. Orthologous to human DLG4 (discs large MAGUK scaffold protein 4).
- Versandbedingungen:
- Blue Ice