A28847
cGAS Rabbit monoclonal antibody
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- SKU:
- A28847
- Zusätzliche Namen:
- E330016A19Rik|Mb21d1
- Anwendung:
- ELISA, WB, IHC-P
- Molekulargewicht:
- 62 kDa
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Uniprot:
- Q8C6L5
- Synonyme:
- 2'3'-cGAMP synthase;C6orf150;cGAMP synthase;cyclic GMP-AMP synthase;E330016A19Rik;h-cGAS;Mab-21 domain containing 1;mab-21 domain-containing protein 1;MB21D1;protein MB21D1
- Weitere Details:
- The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice