PE Rabbit anti-Monkey/Human CD159a monoclonal antibody

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SKU:: A28835
Zusätzliche Namen:: nkg2A
Anwendung:: Flow Cytometry
Spezies-Reaktivität:: Non-human Primate
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Spezies:: Non-human Primate
Synonyme:: C-lectin type II protein;CD159 antigen-like family member A;CD159A;killer cell lectin-like receptor subfamily C, member 1;natural killer cell lectin;natural killer group protein 2;NK cell receptor A;NKG2;NKG2-1/B activating NK receptor;NKG2-A/B type II integral membrane protein;NKG2-A/B-activating NK receptor;NKG2-A/NKG2-B type II integral membrane protein;NKG2A
Weitere Details:: CD159a (also known as NKG2A, encoded by the KLRC1 gene) is an inhibitory receptor on the surface of natural killer (NK) cells and some T cells. After binding to HLA-E molecules, it transmits inhibitory signals to regulate the activity of immune cells. Some viruses (such as HIV and CMV) upregulate the expression of HLA-E to bind to CD159a and inhibit the function of NK cells. Blocking the NKG2A/HLA-E pathway can restore antiviral immunity.