PE Rabbit anti-Human/Monkey CD11b monoclonal antibody

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SKU:: A28771
Zusätzliche Namen:: CD11B|CR3A|HNA-4|MAC-1|MAC1A|MO1A|SLEB6
Anwendung:: Flow Cytometry
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P11215
Synonyme:: antigen CD11b (p170);CD11 antigen-like family member B;CD11B;cell surface glycoprotein MAC-1 subunit alpha;complement component 3 receptor 3 subunit;CR-3 alpha chain;CR3A;integrin alpha-M;integrin, alpha M (complement component 3 receptor 3 subunit);leukocyte adhesion receptor MO1;MAC-1;MAC1A;macrophage antigen alpha polypeptide;macrophage-1 antigen alpha subunit;MO1A;Neutrophil adherence receptor;neutrophil adherence receptor alpha-M subunit;SLEB6
Weitere Details:: The differentiation antigen cluster molecule 11b (CD11b) / integrin A Alpham (ITGAM) is a transmembrane protein that forms a heterodimer composed of A Alpha and B Beta subunits. CD11b is expressed in myeloid cells and is commonly used as a marker for myeloid cells, such as neutrophils, monocytes, macrophages, and microglia. CD11b is phosphorylated at the Ser1126 site (cytoplasmic tail region) in neutrophils. Studies have shown that this phosphorylation activity plays a role in the process of white blood cells transferring from the bloodstream to tissues. Additionally, genome-wide association studies have indicated that CD11b is associated with autoimmune diseases such as systemic lupus erythematosus (SLE).

Versandbedingungen:: Blue Ice