A28756
Anti-Monkey CD16 monoclonal antibody
Größe
£158.00
- SKU:
- A28756
- Zusätzliche Namen:
- CD16|CD16-II|CD16A|FCG3|FCGR3|FCGRIII|FcGRIIIA|FCR-10|FCRIII|FCRIIIA|IGFR3|IMD20
- Anwendung:
- IHC, IHC-P
- Spezies-Reaktivität:
- Non-human Primate
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Synonyme:
- Fc-gamma receptor 3A;Fc-gamma RIII;Fc-gamma RIII-alpha;Fc-gamma RIIIa;fcgammaRIIIa;FCGR;FCGR3;FcRIII;IgG Fc receptor III;IgG Fc receptor III-A;Low affinity immunoglobulin gamma Fc region receptor III;low affinity immunoglobulin gamma Fc region receptor III-A;LOW QUALITY PROTEIN: low affinity immunoglobulin gamma Fc region receptor III
- Weitere Details:
- This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice