APC Rabbit anti-Human HLA-B (MITD Specific) monoclonal antibody

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SKU:: A28686
Zusätzliche Namen:: AS|B-4901|HLAB
Anwendung:: Flow Cytometry
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P01889
Synonyme:: AS;B-4901;HLA class I antigen HLA-B;HLA class I histocompatibility antigen, B alpha chain;HLAB;Human leukocyte antigen B;leukocyte antigen class I-B;major histocompatibility complex, class I, B;MHC class 1 antigen;MHC class I antigen B*7;MHC class I antigen HLA-B alpha chain;MHC class I antigen HLA-B heavy chain;MHC class I antigen SHCHA;MHC class I molecule;MHC HLA-B cell surface glycoprotein;MHC HLA-B transmembrane glycoprotein
Weitere Details:: The human leukocyte antigen (HLA) system is a gene complex encoding the major histocompatibility complex (MHC) proteins in humans. These cell-surface proteins are responsible for the regulation of antigen-specific immune responses in humans. HLA genes are highly polymorphic, which enables them to fine-tune the adaptive immune response. The class I HLA molecules (HLA-A, -B, and -C) present small peptide antigens, approximately 8 to 10 amino acids in length, originating from inside the cell to CD8+ cytotoxic T lymphocytes, thereby activating a cytotoxic T-cell response. The class II HLA molecules (HLA-DP, -DM, -DO, -DQ, and -DR) present antigens derived from outside the cell, approximately 15 to 24 residues in length, to CD4+ helper T cells. These helper T cells subsequently secrete cytokines and stimulate B cells to produce antibodies specific to that antigen. The class III HLA region encodes components of the complement system.

Versandbedingungen:: Blue Ice