APC Rabbit anti-Human CD41 monoclonal antibody

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SKU:: A28635
Zusätzliche Namen:: BDPLT16|BDPLT2|CD41|CD41B|GP2B|GPIIb|GT|GT1|GTA|HPA3|PPP1R93
Anwendung:: Flow Cytometry
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P08514
Synonyme:: alphaIIb protein;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPalpha IIb;GPIIb;GT;GT1;GTA;HPA3;integrin alpha-IIb;integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41);platelet fibrinogen receptor, alpha subunit;platelet glycoprotein IIb of IIb/IIIa complex;platelet membrane glycoprotein IIb;platelet-specific antigen BAK;PPP1R93;protein phosphatase 1, regulatory subunit 93
Weitere Details:: CD41 is the 125 kDa alpha subunit (A AlphaIIb) of the gpIIb/IIIa (CD41/CD61) complex. It exists as a heterodimer composed of a heavy chain (gpIIbA Alpha) and a light chain (gpIIbB Beta) linked by a single disulfide bond. As a member of the integrin family, CD41 is predominantly expressed on platelets and megakaryocytes. It is reportedly involved in platelet aggregation and platelet adhesion to the extracellular matrix (ECM). The CD41/CD61 complex functions as a receptor for fibrinogen, fibronectin, von Willebrand factor, and thrombin.