DOG-1/TMEM16A Rabbit monoclonal antibody

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SKU:: A28584
Zusätzliche Namen:: DOG1|INDMS|MYMY7|ORAOV2|TAOS2|TMEM16A
Anwendung:: ELISA, WB, IHC-P
Molekulargewicht:: 150 kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: Q5XXA6
Synonyme:: anoctamin 1, calcium activated chloride channel;anoctamin-1;Ca2+-activated Cl- channel;calcium activated chloride channel;discovered on gastrointestinal stromal tumors protein 1;DOG1;oral cancer overexpressed 2;Oral cancer overexpressed protein 2;ORAOV2;TAOS2;TMEM16A;Transmembrane protein 16A;transmembrane protein 16A (eight membrane-spanning domains);tumor-amplified and overexpressed sequence 2
Weitere Details:: Enables identical protein binding activity; iodide transmembrane transporter activity; and ligand-gated monoatomic ion channel activity. Involved in several processes, including monoatomic anion transport; mucus secretion; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in apical plasma membrane and nucleoplasm. Implicated in Moyamoya disease.