[KO Validated] GSDME (Full Length+N terminal) Rabbit monoclonal antibody

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SKU:: A28582
Zusätzliche Namen:: 2310037D07Rik|4932441K13Rik|Dfna5|Dfna5h|EG14210|Fin15
Anwendung:: ELISA, WB, IP
Molekulargewicht:: 57 kDa(Full length)/35 kDa(N terminal)
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Mouse
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: Q9Z2D3
Synonyme:: 2310037D07Rik;4932441K13Rik;deafness associated tumor suppressor;deafness, autosomal dominant 5 homolog;Dfn;Dfna;DFNA5;DFNA5, deafness associated tumor suppressor;Dfna5h;EG14210;Fin;Fin15;gasdermin-E;ICERE-1;inversely correlated with estrogen receptor expression 1;non-syndromic hearing impairment protein 5;non-syndromic hearing impairment protein 5 homolog;nonsyndromic hearing impairment protein
Weitere Details:: Enables cardiolipin binding activity. Involved in cellular response to virus and pyroptotic inflammatory response. Acts upstream of or within inner ear auditory receptor cell differentiation. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 5 and sensorineural hearing loss. Orthologous to human GSDME (gasdermin E).