GSDMD (Full Length+N terminal) Rabbit monoclonal antibody

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SKU:: A28573
Zusätzliche Namen:: 1810036L03Rik|DF5L|Dfna5l|GsdmD-1|Gsdmdc1|M2-4
Anwendung:: ELISA, WB
Molekulargewicht:: 31 kDa(N terminal)/53 kDa(Full Length)
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Mouse
Immunogen:: Recombinant protein (or fragment). This information is considered to be commercially sensitive.
Uniprot:: Q9D8T2
Synonyme:: 1810036L03Rik;AW558049;DF5;DF5L;Dfn;Dfna5l;FKSG10;gasdermin domain containing 1;gasdermin domain-containing protein 1;gasdermin-D;gasderminD-1;GsdmD-1;Gsdmdc;Gsdmdc1;M2-4
Weitere Details:: Enables phospholipid binding activity; transcription coactivator activity; and wide pore channel activity. Involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta production; and protein-containing complex assembly. Acts upstream of or within ceramide biosynthetic process; plasma membrane repair; and protein maturation. Located in cytosol; extracellular space; and mitochondrial membrane. Part of NLRP3 inflammasome complex. Is active in plasma membrane. Is expressed in several structures, including aorta; gut; liver; metanephros; and spleen. Orthologous to human GSDMD (gasdermin D).