CD44 Rabbit PolymAb[R]

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SKU:: A28567PM
Zusätzliche Namen:: HERMES|Ly-24|Pgp-1
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 80-95 kDa
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P15379
Synonyme:: AU023126;AW121933;AW146109;CD44 antigen;CDW44;cell surface glycoprotein CD44;chondroitin sulfate proteoglycan 8;CSPG8;ECMR-III;epican;extracellular matrix receptor III;GP90 lymphocyte homing/adhesion receptor;HCELL;hematopoietic cell E- and L-selectin ligand;heparan sulfate proteoglycan;HERM;HERMES;Hermes antigen;homing function and Indian blood group system;HUTCH-I;hyaluronate receptor;IN;Indian blood group antigen;LHR;Ly-2;Ly-24;lymphocyte antigen 24;MC56;MDU2;MDU3;MIC4;Pgp;Pgp-1;PGP-I;Pgp1;phagocytic glycoprotein 1;phagocytic glycoprotein I;soluble CD44
Weitere Details:: Enables cargo receptor activity; hyaluronic acid binding activity; and type II transforming growth factor beta receptor binding activity. Contributes to cytokine binding activity and cytokine receptor activity. Involved in several processes, including hyaluronan catabolic process; negative regulation of T cell activation; and regulation of intracellular signal transduction. Acts upstream of or within several processes, including Wnt signaling pathway; morphogenesis of a branching epithelium; and wound healing involved in inflammatory response. Located in basolateral plasma membrane; external side of plasma membrane; and microvillus. Part of macrophage migration inhibitory factor receptor complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and limb. Human ortholog(s) of this gene implicated in breast carcinoma (multiple); carcinoma (multiple); and prostate cancer. Orthologous to human CD44 (CD44 molecule (IN blood group)).

Versandbedingungen:: Blue Ice