A28508
IRF1 Rabbit polyclonal antibody
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£152.00
- SKU:
- A28508
- Zusätzliche Namen:
- Irf-1
- Anwendung:
- ELISA, WB
- Molekulargewicht:
- 46 kDa
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Uniprot:
- P15314
- Synonyme:
- AU020929;interferon regulatory factor 1;Irf;IRF-1;MAR
- Weitere Details:
- Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including defense response to other organism; regulation of T cell activation; and regulation of gene expression. Acts upstream of or within CD8-positive, alpha-beta T cell differentiation; positive regulation of interleukin-12 production; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including bone marrow; early conceptus; eye; genitourinary system; and gut. Human ortholog(s) of this gene implicated in asthma; immunodeficiency 117; lung cancer (multiple); smallpox; and stomach cancer (multiple). Orthologous to human IRF1 (interferon regulatory factor 1).
- Versandbedingungen:
- Blue Ice