APC/Cyanine7 Rabbit anti-Human CD61 monoclonal antibody

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SKU:: A28504
Zusätzliche Namen:: BDPLT16|BDPLT2|BDPLT24|CD61|GP3A|GPIIIa|GT|GT2
Anwendung:: Flow Cytometry
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P05106
Synonyme:: antigen CD61;BDPLT16;BDPLT2;BDPLT24;CD61;GP3A;GPIIIa;GT;GT2;integrin beta 3;integrin beta chain, beta 3;integrin beta-3;integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61);platelet membrane glycoprotein IIIa
Weitere Details:: CD61, also known as integrin beta 3 and glycoprotein IIIa (gpIIIa), is a 90 kDa type I integral transmembrane glycoprotein. As a member of the integrin family, it associates with platelet glycoprotein IIb (CD41) to form the CD41/CD61 complex (integrin A AlphaIIbB Beta3), and with integrin alpha V (CD51) to form the A AlphaVB Beta3 integrin (CD51/CD61). The CD41/CD61 complex is expressed on platelets and megakaryocytes, where it mediates platelet activation and aggregation through interactions with fibrinogen, fibronectin, von Willebrand factor (vWF), and other RGD-containing adhesion molecules. The CD51/CD61 integrin is expressed on platelets, osteoclasts, fibroblasts, macrophages, and tumor cells involved in metastasis and adenovirus infection, where it binds to RGD motifs present in extracellular matrix proteins.

Versandbedingungen:: Blue Ice