[KO Validated] CD47 Rabbit monoclonal antibody

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SKU:: A28498
Zusätzliche Namen:: 9130415E20Rik|B430305P08Rik|IAP|Itgp
Anwendung:: ELISA, WB, IHC-P
Molekulargewicht:: 40-60 kDa
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: Q61735
Synonyme:: 9130415E20Rik;AA407862;AI848868;antigen identified by monoclonal antibody 1D8;antigenic surface determinant protein OA3;AW108519;B430305P08Rik;CD47 antigen (Rh-related antigen, integrin-associated signal transducer);CD47 glycoprotein;IAP;integrin associated protein;integrin-associated protein;integrin-associated signal transducer;It;Itgp;leukocyte surface antigen CD47;MER6;OA3;Rh-related antigen
Weitere Details:: Predicted to enable protein binding activity involved in heterotypic cell-cell adhesion and thrombospondin receptor activity. Involved in positive regulation of activation-induced cell death of T cells; regulation of nitric oxide biosynthetic process; and regulation of synapse pruning. Acts upstream of or within several processes, including monocyte aggregation; opsonization; and positive regulation of phagocytosis. Located in extracellular exosome and plasma membrane. Is active in glutamatergic synapse and presynapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human CD47 (CD47 molecule).

Versandbedingungen:: Blue Ice