USP15 Rabbit monoclonal antibody

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SKU:: A28494
Zusätzliche Namen:: UNPH-2|UNPH4
Anwendung:: ELISA, WB, IP
Molekulargewicht:: 120 kDa
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: Q9Y4E8
Synonyme:: deubiquitinating enzyme 15;ubiquitin carboxyl-terminal hydrolase 15;ubiquitin thioesterase 15;ubiquitin thiolesterase 15;ubiquitin-specific-processing protease 15;UNPH-2;UNPH4
Weitere Details:: This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2.