ZO-1 Rabbit monoclonal antibody

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SKU:: A28491
Zusätzliche Namen:: ZO1
Anwendung:: ELISA, WB, IHC-P, IF, ICC
Molekulargewicht:: 250 kDa
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P39447
Synonyme:: Tight junction protein 1;tight junction protein ZO-1;ZO;ZO-;ZO-1;ZO1;zona occludens 1;zona occludens protein 1;zonula occludens 1 protein;zonula occludens protein 1
Weitere Details:: Enables connexin binding activity and protein domain specific binding activity. Involved in several processes, including ameloblast differentiation; negative regulation of stress fiber assembly; and positive regulation of sprouting angiogenesis. Acts upstream of or within blastocyst formation and sensory perception of sound. Located in several cellular components, including apicolateral plasma membrane; bicellular tight junction; and intercellular canaliculus. Part of protein-containing complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Orthologous to human TJP1 (tight junction protein 1).