APC Rabbit anti-Human CD123 monoclonal antibody

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SKU:: A28487
Zusätzliche Namen:: CD123|hIL-3Ra|IL-3R-alpha|IL3R|IL3RAY|IL3RX|IL3RY
Anwendung:: Flow Cytometry
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P26951
Synonyme:: CD123;CD123 antigen;hIL-3Ra;IL-3 receptor subunit alpha;IL-3R subunit alpha;IL-3R-alpha;IL-3RA;IL3R;IL3RAY;IL3RX;IL3RY;interleukin 3 receptor, alpha (low affinity);interleukin-3 receptor subunit alpha
Weitere Details:: CD123 is the 70 kDa transmembrane alpha chain of the interleukin-3 (IL-3) receptor. It binds IL-3 with low affinity when alone; however, upon association with CD131 (the common beta chain), the complex binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon IL-3 binding and requires the beta chain for this function. CD123 is expressed on bone marrow precursor cells, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and certain B-cell populations.