PE Rabbit anti-Mouse CD18 monoclonal antibody

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SKU:: A28461
Zusätzliche Namen:: 2E6|Cd18|LAD|LCAMB|Lfa1|MF17
Anwendung:: Flow Cytometry
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: P11835
Synonyme:: 2E6;AI528527;CD18;cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor);cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;complement component 3 receptor 3 and 4 subunit;complement receptor C3 beta-subunit;complement receptor C3 subunit beta;integrin beta chain, beta 2;integrin beta-2;integrin, beta 2 (complement component 3 receptor 3 and 4 subunit);LAD;LCAMB;leukocyte cell adhesion molecule CD18;leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C;LFA-1;Lfa1;lymphocyte function associated antigen 1;MAC-1;Mac-1 beta;macrophage antigen-1 beta;MF17;MFI7;truncated integrin beta-2
Weitere Details:: CD18, also known as the integrin beta 2 subunit. It is expressed on all leukocytes. CD18 associates with integrin alpha chains CD11a, CD11b, and CD11c to form LFA-1 (CD11a/CD18), Mac-1 (CD11b/CD18), and A AlphaXB Beta2 (CD11c/CD18), respectively, playing a critical role in leukocyte adhesion. The CD18 integrin complexes bind to ligands such as ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is capable of blocking tumor cell metastasis and enhancing cell adhesion.

Versandbedingungen:: Blue Ice