Caspase-8 Rabbit monoclonal antibody

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SKU:: A28460
Zusätzliche Namen:: CASP-8|Caspase-8|FLICE|MACH|Mch5
Anwendung:: ELISA, WB, IF, ICC, IP
Molekulargewicht:: 57 kDa(pro)/43 kDa(cleavad)
Spezies-Reaktivität:: Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Abclonal
Host:: Rabbit
Reaktivitäten:: Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulierung:: Unmodified
Uniprot:: O89110
Synonyme:: ALPS2B;apoptotic cysteine protease;apoptotic protease Mch-5;CAP4;Casp;Casp-8;caspase 8, apoptosis-related cysteine peptidase;caspase 8, apoptosis-related cysteine protease;caspase-8;FADD-homologous ICE/CED-3-like protease;FADD-like ICE;Fas-linked ICE-like protease;FLI;FLICE;ICE-like apoptotic protease 5;MAC;MACH;MACH-alpha-1/2/3 protein;MACH-beta-1/2/3/4 protein;MCH5;MORT1-associated ced-3 homolog
Weitere Details:: This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, an initiator of apoptotic cell death, is activated by death-inducing tumor necrosis family receptors and targets downstream effectors. In mouse deficiency of this gene can cause embryonic lethality. This protein may have a role in embryogenesis. Alternative splicing results in multiple transcript variants that encode different protein isoforms.