A28459
HDAC6 Rabbit monoclonal antibody
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- SKU:
- A28459
- Zusätzliche Namen:
- Hd6|Hdac5|mHDA2|Sfc6
- Anwendung:
- ELISA, WB, IHC-P, IF
- Molekulargewicht:
- 130-170 kDa
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Abclonal
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Immunogen:
- Recombinant protein. This information is considered to be commercially sensitive.
- Formulierung:
- Unmodified
- Uniprot:
- Q9Z2V5
- Synonyme:
- CPBHM;HD6;Hdac5;histone deacetylase 5;histone deacetylase 6;histone deacetylase mHDA2;JM21;mHDA;mHDA2;PPP1R90;protein phosphatase 1, regulatory subunit 90;scurfy candidate 6;Sfc;Sfc6;tubulin-lysine deacetylase HDAC6
- Weitere Details:
- Enables several functions, including cytoskeletal protein binding activity; protein lysine deacetylase activity; and ubiquitin binding activity. Involved in several processes, including positive regulation of type 2 mitophagy; protein destabilization; and tubulin deacetylation. Acts upstream of or within several processes, including aggresome assembly; neuron projection morphogenesis; and protein modification process. Located in several cellular components, including dendrite; microtubule cytoskeleton; and perikaryon. Part of cytoplasmic ubiquitin ligase complex. Is expressed in several structures, including central nervous system; early embryo; gut gland; lung; and metanephros. Human ortholog(s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia and polycystic liver disease 1. Orthologous to human HDAC6 (histone deacetylase 6).
- Versandbedingungen:
- Blue Ice